The Vital Role of the Liver
The liver plays a crucial role in maintaining our body's well-being. Its functions include:
- Nutrient Metabolisation: Transforming nutrients into more accessible forms for the body.
- Detoxification: Eliminating toxic substances and foreign bodies.
- Nutrient Storage: Preserving vitamins, minerals, glucose, and iron.
- Fat and Cholesterol Management: Overseeing fat storage and cholesterol utilisation.
- Blood Clot Regulation: Contributing to blood clotting processes.
- Energy Production: Generating energy, immune factors, hormones, and blood plasma proteins.
When hepatitis infects the liver, it can significantly impair these vital functions.
Common Causes of Hepatitis
Hepatitis, a condition characterised by liver inflammation, can stem from various sources:
- Viral Infections: A leading cause of hepatitis.
- Lifestyle Factors: Excessive alcohol consumption.
- Infections: Bacterial, protozoan, and leptospirosis infections.
- Parasites: Contributing to liver inflammation.
- Medications and Chemicals: Certain types can damage liver cells.
Types of Hepatitis Viruses and Their Characteristics
Hepatitis viruses vary in their nature and impact:
- Hepatitis A (HAV): Common in older children and adults, usually resolving without leading to chronic liver disease. A vaccine is available.
- Hepatitis B (HBV): Often symptom-free, with potential to become chronic or turn the person into a carrier. Vaccination is available.
- Hepatitis C (HCV): Typically asymptomatic, but can lead to cirrhosis and liver cancer. No vaccine is currently available.
- Hepatitis D (HDV): Co-occurs with HBV and can cause severe hepatitis.
- Hepatitis E (HEV): Not prevalent in Thailand, but common in neighbouring regions.
- Hepatitis G (HGV): Transmitted through blood and sexual contact.
Identifying Common Symptoms of Hepatitis
Hepatitis can present a range of symptoms, often similar to the flu, including:
- General Discomfort: Fatigue, body and muscle aches, joint pain.
- Digestive Issues: Nausea, vomiting, loss of appetite.
- Fever and Headaches: Reflecting the body's response to infection.
- Specific Signs: Abdominal tenderness, right rib pain, pale stools, dark urine.
- Jaundice: Yellowing of skin and eyes, possibly accompanied by itching.
While most patients recover, hepatitis B can lead to chronic conditions in some cases.
Approach to Hepatitis Diagnosis
Diagnosis typically involves a combination of clinical assessment and specific tests:
- Symptom Evaluation: Recognising the signs mentioned above.
- Physical Examination: Checking for physical indicators of liver issues.
- Blood Tests: Including Liver Function Test (LFT) and specific hepatitis virus tests, detecting markers like SGOT, SGPT, and bilirubin levels.
- Virus-Specific Tests: Differentiating between various hepatitis viruses through immunoglobulin and antigen tests.
Handling Acute Hepatitis Symptoms
While specific treatment for hepatitis is limited, symptom management is crucial:
- Rest: Essential for combating fatigue.
- Dietary Adjustments: Light, low-fat meals to ease digestion.
- Medical Intervention: Medications for severe symptoms like vomiting or itching.
- Avoiding Liver Stressors: Staying clear of alcohol and certain medications.
Chronic Hepatitis Treatment and Effective Prevention
Addressing Chronic Hepatitis
Chronic hepatitis, particularly from HBV and HCV, requires careful management:
- Treatment for HBV: Tailored medication plans by gastroenterologists or hepatologists, considering the patient's condition and medical history.
- Handling HCV: Determining the virus strain and treatment duration is vital, alongside tests like FibroScan or liver biopsy, to assess infection status before treatment initiation.
Preventive Measures Against Hepatitis
Prevention plays a key role in reducing hepatitis risk:
- Hygiene Practices: Regular hand washing and consuming well-cooked food and clean water.
- Safe Practices: Avoiding contact with others' bodily fluids, not sharing personal items, and practising safe sex.
- Vaccination: Vaccines are available for Hepatitis A and Hepatitis B.
Recurrence Patterns in Different Hepatitis Types
- Hepatitis A and Hepatitis E: Typically resolve on their own without recurrence.
- Hepatitis B: Over 90% of patients recover with immunity against recurrence.
- Hepatitis C and Hepatitis D: Recurrence possibilities are less clear due to limited information.
Persistent Infection Risk
While symptoms may improve or disappear, the virus can remain, posing a risk of future liver damage. This risk is mitigated by the body's antibody response, which becomes more robust once symptoms improve.
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